View AbstractLife is the most important gift from God. Everything becomes beautiful when an individual is health both physically and mentally. For an economically sound individual, dealing with any health problems is to some extent easy when it comes to negotiating with the health related expenditures , but for an individual who is economically weak, illness appears difficult and stressful and almost impossible to manage especially if the health problem is severe and not curable like Down syndrome. In such situations people often resort to seek help from the religion. In case of Muslims, the belief is that whatever Allah bestows upon them is best for them. Among Muslims having children with Down syndrome is considered a curse for the parents, while in some other societies it is considered reward from God. So the perceptions vary while interpreting the phenomenon of Down syndrome. Despite different interpretations, the socio-economic burden of the disease remains the same. The present paper focuses on those parents whose children are suffering from Down syndrome and are working in unorganised/ informal sector as workers in this sector generally lack any public funded social security support, therefore have low economic status. The research has been carried out not only to study socio-economic problems of parents with children having Down syndrome but also to study the various coping strategies parents adopt in order to deal with the problem. So far the present research is concerned; it has been carried out in district Srinagar. Qualitative method has been used in order to gather the data.